Research

Inclusion of all projects (funded and non-funded)

 

            Projects: Primary Investigator- last 5years (Dr Anshu)

 

  1. Budd Chiari syndrome in children: medium and long-term outcome with and without radiological intervention.—completed, published
  2. Endoscopic variceal ligation alone or in combination with non-selective beta blocker for secondary prophylaxis in children with portal hypertension- A Randomized control trial –
  3. Risk factors and early prediction of Post-Endoscopic Retrograde Cholangio--pancreatography Pancreatitis (PEP) in children- completed, published
  4. Role of visceral fat quantification in differentiating Crohn's disease from Intestinal tuberculosis in children-completed, published
  5. Multicentric, cross sectional study of quality of life in children with chronic pancreatitis - completed, published
  6. Cirrhotic cardiomyopathy in children with chronic liver diseases: Correlation with severity of liver disease and its effect on outcome. Intramural project- funded by SGPGIMS Rs 9.6 lac, Project complete. Analysis to be done
  7. Thrombophilic disorders in children with Budd Chiari syndrome- prevalence, nature and effect on clinical presentation and response to treatment, Intramural project- funded by SGPGIMS Rs 10/lac, Ongoing project
  8. Aggressive hydration with ringer lactate versus ringer lactate with indomethacin in prevention of post ERCP pancreatitis in children: A randomized trial. Coinvestigator - Ongoing project
  9. Clinical profile, response to therapy and outcome of children with Progressive Familial Intrahepatic Cholestasis (PFIC) and its relation to the genetic mutation. Coinvestigator - Ongoing project
  10. Natural history and non-transplant outcome of children with compensated or decompensated chronic liver disease - Ongoing project
  11. Natural history and predictors of response to therapy in children with autoimmune liver disease. Ongoing project
  12. Clinical features, response to therapy and outcome in pediatric cyclical vomiting syndrome: Experience from the developing world. - completed, published
  13. Comparative Efficacy of Carvedilol and Propranolol in the Management of Portal Hypertension in Children with Chronic Liver Disease. - Ongoing project.
  14. Long-Term Outcomes After Moderately Severe and Severe Acute Pancreatitis in Children: A Single-Center Retrospective Cohort Study. - Ongoing project
  15. CMV and IBD in children- clinical features and effect on outcome. Ongoing project
  16. Histological findings and clinical correlates of PSVD. Ongoing project
  17. Prophylactic EVL in children with portal hypertension. Ongoing project

 

Projects: Primary Investigator- (Dr Moinak)

 

Funded projects

 

Title

Funding Agency

Grant Amount

(INR)

Duration and

Date of Start

1.      

Sibling screening of children with Wilson disease by genetic testing

Intramural grant, SGPGIMS

10 lakhs

Ongoing

2.      

Genotype-phenotype correlation with the efficacy of chelation therapy in pediatric hepatic Wilson disease in North India

Dept of Health Research (Indian Council of Medical Research)

53 lakhs

Ongoing

3.      

Hepatic parenchymal extinction in extrahepatic portal venous obstruction

Intramural grant, SGPGIMS

10 lakhs

Ongoing

4.      

Genome-wide transcriptome analysis and its correlation with phenotype in hepatic Wilson disease

Intramural grant, SGPGIMS

10 lakhs

Ongoing

5.      

 

 Evaluation of renal tubular dysfunction in Wilson Disease

Uttar Pradesh Council of Science and Technology

15 lakhs

Ongoing

6.      

Evaluation of glycemic and metabolic control by continuous glucose monitoring in children with hepatic glycogen storage disease: A prospective cohort study

Intramural grant, SGPGIMS

5 lakhs

Ongoing

7.      

Evaluation of Occult Renal Dysfunction using Functional Magnetic Resonance Imaging in Patients with Cirrhosis

Intramural grant, SGPGIMS

5 lakhs

Ongoing

8.      

Can we improve management of occult neurological changes in patients with hepatic Wilson disease?

Intramural grant, SGPGIMS

5 lakhs

Ongoing

9.      

Screening of Iron overload in Wilson disease

DM student project (prospective)

-

Ongoing

10.   

Assessment of sarcopenia and its correlation with pancreatic fibrosis in children with Chronic pancreatitis

DM student project (prospective)

-

Ongoing

11.   

Intestinal Permeability and Bacterial Translocation in Spontaneous Bacterial Peritonitis in Children

Intramural grant

 SGPGIMS

5 lakhs

Start 1.7.2021

 Completed Aug 2023

12.   

Relative adrenal insufficiency in children with chronic liver disease and effect of albumin therapy

 

Intramural grant, SGPGIMS

4.5 lakhs

2 years

Sanctioned and started on 16.10.2017

Completed. Manuscript published

13.   

Assessment of selenium deficiency in gluten-free diet in patients with celiac disease

 

Intramural grant, SGPGIMS

5 lakhs

2 years

Sanctioned and started on 19.6.2018

Completed

14.   

The efficacy of Exchangeable copper and Relative Exchangeable Copper (REC) in the assessment of chelation in children with Hepatic Wilson’s disease

 

DM student project (prospective)

None

2 years

Sanctioned and started on 14.8.2018

Completed

 

 Non-funded projects (Dr. Moinak Sen Sarma)

  1. Clinical spectrum and diagnostic approach to monogenic protein-losing enteropathy in children
  2. Clinical profile, hepatic and extrahepatic outcomes in galactosemia patients
  3. Bile acid synthetic disorders: clinical profile and natural history
  4. Profile of children with cryptogenic multifocal ulcerostenosing small bowel enteropathy (CMUSE)
  5. Nephropathy following portosystemic shunt surgery
  6. Clinical profile and natural history of congenital hepatic fibrosis in children
  7. Intraoperative endoscopy in children
  8. Outcomes of gastric and duodenal varices in children with portal hypertension: a retrospective cohort study.
  9. Outcomes of corrosive strictures in children
  10. Pediatric hepatic Wilson disease: Experience from a tertiary care center
  11. Natural history and outcome of acute liver failure
  12. Endosonography in children
  13. ERCP in children : Indications and outcome
  14. Analysis of patients with recompensated cirrhosis