Selected Publications

  1. Gajendra Singh, Alok Kumar. Japanese Encephalitis Virus Infection Causes an Imbalance in the Activation of Mitochondrial Fusion/Fission Genes and Triggers the Activation of NOX2-mediated Oxidative Stress and Neuronal Cell Death. Neurochem Res. 2023 Mar 1. doi: 10.1007/s11064-023-03898-9. Epub ahead of print. PMID: 36856962, *Corresponding author
  2. Devlina Ghosh , Bingxin Bai, Qun Ji, Soumya Palliyil, Guang Yang, Alok Kumar, Abhishek Saxena#. State-of-the-art preclinical evaluation of COVID-19 vaccine candidates. Explor Immunol. 2021;1:440-60,
  3. Rajni Sharma, Manju Kumari, Suman Mishra, Dharmendra K. Chaudhary, Alok Kumar, Batia Avni, Swasti Tiwari. Exosomes Secreted by Umbilical Cord Blood-Derived Mesenchymal Stem Cell Attenuate Diabetes in Mice, Journal of Diabetes Research, 2021, 9534574.
  4. Alok Kumar, J Kalita, Rohit A Sinha, Anjum B, Mukti Shukla, Swasti Tiwari, T N Dhole, U K Misra. Impaired Autophagy Flux is Associated with Proinflammatory Microglia Activation Following Japanese Encephalitis Virus Infection. Neurochem Res, 45:2184-2195, 2020, "Corresponding author.
  5. Sneha Ghildiyal, Tanzeem fatima, Dharamveer Singh, Shivbrat Upadhyay, Tapan N. Dhole, D. Himanshu Reddy#, Alok kumar, Pro-inflammatory and anti-inflamatory cytokine genes polymorphisms and susceptibility to Japanese encephalitis disease in the North Indian population. Cytokine, 2021 Oct 9;149:155716. doi: 10.1016/j.cyto.2021.155716.,*Corresponding author.
  6. Swati Singh, Gajendra Yadav, Swasti Tiwari, Alok Kumar . CCR2 Inhibition Reduces Neurotoxic Microglia Activation Phenotype After Japanese Encephalitis Viral Infection. Front Cell Neurosci, 14:230, 2020, *Corresponding author.
  7. Aditya Upadhyay, Rohit Sinha, Alok Kumar, Madan Godbole. Time-restricted feeding ameliorates maternal high-fat diet induced fetal lung injury. Exp Mol Pathol. 114:104413, 2020.
  8. U K Misra, Sandeep Singh, J Kalita, Alok Kumar. Astrocyte activation following nitrous oxide exposure is related to oxidative stress and glutamate excitotoxicity, Brain Research,1730:146645, 2020.
  9. J Kalita, U. K. Misra, Alok Kumar. Customized autophagy: a long way to go. Neuroimmunol Neuroinflammation, 5:16, 2018.
  10. Chinmoy Sarkar, Jace W. Jones, Nivedita U. Hegdekar, Julia A. Thayer, Alok Kumar, Alan I. Faden, Maureen A. Kane, Marta M. Lipinski. PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma. Autophagy, 16(3):466-485, 2020.
  11. Boris Sabirzhanov, Yun Li, Marino Coll-Miro, Jessica J. Matyas, Junyun He, Alok Kumar, Nicole Ward, Jingwen Yu, Alan I. Faden, Junfang Wu. Inhibition of NOX2 signaling limits neuropathic pain and improves motor function after spinal cord injury through modulation of IL-10/miR-155 pathways. Brain Behavior Immunity 80:73-87, 2019.
  12. Alok Kumar, Bogdan A Stoica, David J Loane, Ming Yang, Gelareh Abulwerdi, Niaz Khan, Asit Kumar, Stephen R Thom, Alan I Faden. Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury, Journal of Neuroinflammation, 14(1):47, 2017.
  13. James P. Barrett, Rebecca J. Henry, Sonia Villapol, Alok Kumar, Bogdan A. Stoica, Mark P. Burns, Alan I. Faden, and David J. Loane. NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for acute brain injury, Journal of Neuroinflammation,14:65, 2017.
  14. Alok Kumar,James P. Barrett, Dulce-Mariely Alvarez-Croda, Bogdan A. Stoica, Alan I. Faden, David J. Loane. NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury, Brain Behavior Immunity, 58:291-309, 2016.
  15. Jacob W Skovira, Junfang Wu, Jessica J Matyas, Alok Kumar, Marie Hanscom, Shruti V Kabadi, Raymond Fang, Alan I Faden. Cell cycle inhibition reduces inflammatory responses, neuronal loss and cognitive deficits induced by hypobaria exposure following traumatic brain injury, Journal of Neuroinflammation, 13(1):299, 2016.
  16. Junfang Wu*, Zhauri Zhao*, Alok Kumar, David J Loane, Bogdan Stoica, Alan Faden. Endoplasmic Reticulum Stress and Disrupted Neurogenesis in the Brain Are Associated with Cognitive Impairment and Depressive-Like Behavior after Spinal Cord Injury. *equal authorship, Journal of Neurotrauma, 33(21):1919-1935, 2016.
  17. Alok Kumar,Bogdan A. Stoica, Alan I. Faden, David J. Loane. Macrophage/ microglia polarization dynamics during acute brain injury in mice, Journal of Neurotrauma, 33(19):1732-1750, 2016.
  18. David J. Loane, Alok Kumar,Microglia in the TBI Brain: The Good, The Bad, and The Dysregulated. Experimental Neurology, 275, 316-327, 2016.
  19. David Loane, Bogdan Stoica, Flaubert Tchantchou, Alok Kumar, James P. Barrett, Titilola Akintola, Fengtian Xue, P. Jeffrey Conn, Alan Faden. Novel mGluR5 positive allosteric modulator improves functional recovery, attenuates neurodegeneration, and alters microglial polarization after experimental TBI. Neurotherapeutics, 11(4):857-69, 2014.
  20. Junfang Wu, Zaorui Zhao, Boris Sabirzhanov, Bogdan A. Stoica, Alok Kumar, Tao Luo, Jacob Skovira, Alan I. Faden. Spinal cord injury causes brain inflammation associated with cognitive and affective changes: role of cell cycle pathways. Journal of Neuroscience,34(33):10989-1006, 2014.
  21. Also published in Science Daily Report, "Do spinal cord injuries cause subsequent brain damage? ", 2014.

  22. Alok Kumar, Bogdan A. Stoica, Boris Sabirzhanov, Mark P. Burns, Alan I. Faden, David J. Loane. Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states.Neurobiology of Aging, 34(5):1397-411, 2013.

  23. David J. Loane,Alok Kumar, Bogdan A. Stoica, Rainier Cabatbat, Alan I. Faden. Progressive neurodegeneration after experimental brain trauma; association with chronic microglial activation., Journal of Neuropathology and Experimental Neurology, 73(1), 14-29, 2014.

  24. Alok Kumar, David J Loane. Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention.Brain Behavior Immunity, 26(8):1191-201, 2012.

    Published Book Chapters

    1. Alok Kumar, Ved Prakash Maurya. Cellular and Molecular Immune Response to Traumatic Brain Injury. Textbook of Traumatic Brain Injury, Third edition, NP Publication, 2023 (in press).

    2. Gajendra Yadav, Divisha Rao, Alok Kumar. Molecular Basis of Neurological Disorders. The Molecular Immunology of Neurological Diseases, 1st edition, Elsevier (Academic Press; Pages 1-13, *ISBN: 9780128219744; https://doi.org/10.1016/B978-0-12-821974-4.00014-5), 2021.

    3. Devlina Ghosh, Alok Kumar, Neeraj Sinha. Targeted genome editing: a new era in molecular biology. Advances in Animal Genomics, Elsevier (Academic Press; Pages 75-89, *ISBN: 9780128205952 ; https://doi.org/10.1016/B978-0-12-820595-2.00006-0), 2021.

    4. Alok Kumar, Swasti Tiwari, Amit Goel. Management of Inflammatory Bowel Disease (IBD) by Probiotics-Biofilms, Biofilms in Human Diseases: Treatment and Control, Springer Nature (Pages 299-311, ISBN : 978-3-030-30756-1; DOI: 10.1007/978-3-030-30757-8_19), 2019.