Core Lab

Common Research Facility (Core Lab) – Functioning Report

Part I. Past and Present

A. Establishment of Common Research Facility The Common Research Facility (CRF, Core Lab) was established as an extramural project funded by Department of Biotechnology (DBT), New Delhi, granted in 2003, titled “Establishment of Advanced Biomedical Research Facility” by the Heads of the Departments of Immunology (Prof SitaNaik) and Nephrology (Prof RK Sharma).The project was granted for 3 years with a total budget of Rs.169.27 lakhs. Later it was named as Central Research Facility,commonly known as Core Lab within the institute. • Central research facility is a requirement by MCI for recognition of a medical college/institute as per “Minimum Standard Requirements for Medical College, Regulations 1999”, updated as per the terms of notification published on 02.12.2008 in the Gazette of India (page 9, point no. A.1.19b, Annexure I) and latest “Standard Assessment Form” for year 2020-21 by MCI (page 10, Part-I, point no. 5, Annexure II).

B. Location The extramural project was granted in 2003, however, the current location on 2nd floor of New Diagnostic block in C-Block became functionally active by 2006 and actual molecular work started in Core Lab from 2009. Since thentill Dec 2018, Core Lab was functioning with 6 roomson one side of the corridor. The rooms on other side of the corridor was being temporarily used by Department of Clinical Hematology as stem cell research lab.In Sept 2018, one room was vacated by Department of Clinical Hematology for housing sequencers and other room was vacated in Jun 2019 for housing LCMS (Liquid Chromatography Mass Spectrophotometry) which after renovation became functional in Dec 2018 and Sept 2019 respectively. At present the Core Lab is functional in 8 rooms/labs on both sides of the corridor on 2nd floor, New Diagnostic Block.

C. Research Facilities The activities in Core Labstarted with basic molecular biology such as nucleic acid extraction, electrophoresis, conventional PCR, ELISA-multimode, western blot, and providing miliQ water to different laboratories and clinical departments from 2009. Later gradually more facilities were created under the chairmanship of different faculty as mentioned in table 1. Core Lab provides and maintains infrastructure facilities andthe reagents are to be procured by the researchers.

After end of the DBT funded project, the routine maintenance and day to day expenses are met from Research Endowment fund. In an attempt to optimally utilize the available facilities and provide support to research students of the institute as well as other universities, short-term training (3-6 months) was started from Jan 2012 during the tenure of Prof RK Gupta (Radiology) as chairman and Prof RK Sharma (Nephrology) as Director. The training charges are as per institute observership rules (Rs. 5000 for one month,Rs. 10000 up to 3 months and Rs. 15000 up to 6 months). The distribution of training fee as decided by then chairman and Director in 2012 is 40% to the Research Endowment Fund and 60% to Core Lab fund for procuring reagents for training. Students are enrolled through Research Cell after approval from the Director and a certificate after completion is issued from the Dean/Director through the Research Cell.