Publications

  1. Khandpur S, Bharadwaj M., Awasthi A., Newtonrajc A., Purty A., Khanna T., Abraham G., and Tiwari S* Association of kidney functions with a cascade of care for diabetes and hypertension in two geographically distinct Indian cohorts. Diabetes Res Clin Pract. 2021 Jun 1;176:108861.
  2. Srivastava A, Srivastava P, Mathur S, Abbas S, Rai N, Tiwari S, Tiwari M, Sharma L. Lipid metabolism and mitochondria: Cross talk in cancer. Curr Drug Targets. 2021 Aug 24. doi: 0.2174 / 1389450122666210824144907.
  3. Sharma R and Tiwari S. Renal gluconeogenesis in insulin resistance: A culprit for hyperglycemia in diabetes. World Journal of Diabetes submitted in February 2021. World J Diabetes 2021 May 15; 12(5), DOI: 10.4239/wjd.v12.i5.0000 ISSN 1948-9358 (online)
  4. Joshi K, Cameron F, Tiwari S, Mannering S.I, Elefanty A.G, Stanley E.J. Modelling Type 1 Diabetes using Pluripotent Stem Cell Technology has been approved for production and accepted for publication in Frontiers in Endocrinology, section Diabetes: Molecular Mechanisms. Accepted on March 3rd . Frontiers in Endocrinology, section Diabetes: Molecular Mechanisms.
  5. Yadav S., Khandpur S., Yadav YS., Goel MM., Singh U, Natu S.M, Negi MPS., Sharm LK., Tiwari S* Model for early prediction of Preeclampsia: A Nested Case Controlled Study in Indian Women.J Obs and Gyne India (in press June 2021).
  6. Agarwal J, Singh V, garg J, Karoli R, Tiwari S, Naqvi S, Das A, and Sen M. RNAemia and Clinical Outcome in COVID-19 Patients. Journal of Microbiology and Infectious Diseases, 116 - 123, 15.09.2021
  7. Li L, Chelsee Holloway C, Lee H, Sharma R, Tiwari, S, Ecelbarger CM*. Protective Effect of 17β Estradiol against Kidney Injury in a Mouse Model of Unilateral Renal Ischemia. J Nephrol Renal Ther 2021, 7: 046; DOI: 10.24966/NRT-7313/100046
  8. Tiwari S*, Kumar V, Randhawa S and Kumar S. Preparation and characterization of Extracellular Vesicles. American Journal of Reproductive Immunology 2020 (DOI:https://doi.org/10.1111/aji.13367)
  9. Awasthi M., Gulati S., Sarkar D.P., Tiwari S, Kateriya S., Ranjan P., Verma S.K*. The Sialoside-binding pocket of SARS-CoV-2 spike glycoprotein structurally resembles MERS-CoV. Viruses 2020, 12(9), 909; https://doi.org/10.3390/v12090909.
  10. Kumar V, Mishra S, Sharma R, Agarwal j, Ghoshal U, Khanna T, Sharma LK, Verma SK, Tiwari S*. Development of RNA-based assay for rapid detection of SARS-CoV-2 in clinical samples. Doi: https://doi.org/10.1101/2020.06.30.172833
  11. Singh S. Abbas S, Saxena AK, Tiwari S, Sharma LK, Tiwari M. Critical role of 3-dimensional tumorsphere size on experimental outcome" BioTechniques (accepted on July 27th, 2020)
  12. Fluitt M, Shivapurkar N, Kumari M, Singh S, Li L, Tiwari S, and Ecelbarger C. Systemic Inhibition of miR-451 Increases Fibrotic Signaling and Diminishes Autophagic Response to Exacerbate Renal Damage in Tallyho/Jng Mice. (AJP-renal – accepted in July 2020).
  13. Aljaylani A, Fluitt M, Piselli M, Shepard MD, Tiwari S, Ecelbarger CE. Acid Loading unmasks glucose homeostatic instability in proximal-tubule-targeted insulin/insulin-like-growth-factor-1 receptor dual knockout mice. Cellular Physiology and Biochemistry- – accepted in July 2020
  14. Singh S, Singh G, Tiwari S, and Kumar A. CCR2 inhibition reduces neurotoxic microglia activation phenotype following Japanese Encephalitis viral infection. Frontiers in Cellular Neuroscience, section Non-Neuronal Cells (13 August 2020 | https://doi.org/10.3389/fncel.2020.00230).
  15. Kumar A, Kalita J, Sinha RA, Singh G, Anjum B, Shukla M and Tiwari S. Impaired autophagy flux is associated with proinflammatory microglia activation following Japanese encephalitis virus infection. Journal Neurochemical research accepted in June 2020).
  16. Rajak S, Hussain Y, Singh K, Tiwari S, Ahmad B, Bharti S, Prakash P. Cellular Fibronectin Containing Extra Domain A Causes Insulin Resistance via Toll-like Receptor 4. Scientific Reports (Nature publishing)- Accepted on May 7th, 2020.
  17. Kumari M, Mohan A, Singh S, Ecelbarger CA, Gupta A, Prasad, N., and Tiwari S*. MiR-451 loaded exosomes are released by the renal cells in response to injury and associated with reduced kidney function in human. Frontiers in Physiology-renal 2020 Apr 8;11:234. doi: 10.3389/fphys.2020.00234
  18. Sharma R, Kumari M, Prakash P, Gupta S, and Tiwari S* Phosphoenolpyruvatecarboxykinase in urine exosomes reflect impairment in renal gluconeogenesis in earlyinsulin resistance and diabetes accepted on January 29, 2020 in American Journal of Physiology-renal (AJP-renal). 2020 Mar 1;318(3):F720-F731. doi: 10.1152/ajprenal.00507.2019.
  19. Godbole NM, Sinha RA, Tiwari S, Pawar SD, Dhole TN. Analysis of influenza virus-induced perturbation in autophagic flux and its modulation during Vitamin D3 mediated anti-apoptotic signaling. Virus Res. 2020 Jun;282:197936. doi: 10.1016/j.virusres.2020.
  20. Singh RS, Gautam J, Pradhan A, Chaudhary DK, Trivedi R, and Tiwari S*. Benefits of Cholesterol-lowering on bone microarchitecture in hypercholesterolemic diabetic rats. Journal of Molecular Biology & Therapeutics 2019, accepted on November 1st, 2019.
  21. Upadhyay A, Anjum B, Godbole NM, Rajak S, Shukla P, Tiwari S, Sinha RA, Godbole MM. Time-restricted feeding reduces high-fat diet associated placental inflammation and limits adverse effects on fetal organ development. Biochem Biophys Res Commun. 2019 Jun 25;514(2):415-421. doi: 10.1016/j.bbrc.2019.04.154. Epub 2019 May 1.
  22. Singh S, Sharma, S, Kumari M, and Tiwari S*. Insulin receptors in the kidneys in health and disease. World J Nephrol 2019 January 10; 8(1): 11-22
  23. Kumari M, Sharma R, Pandey G, Ecelbarger C, Prabhaker M, Tiwari S*. Deletion of insulin receptor in the proximal tubule and fasting augment albumin excretion. Journal of Cellular Biochemistry ; 2019 Jan 15. doi: 10.1002/jcb.28359.
  24. Minimal Information for Studies of Extracellular Vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Théry C., Witwer K.W, et al. Journal of Extracellular Vesicles 2018 Nov 23;7(1):1535750.
  25. Fluitt M., Rizvi S., Li L., Alunan A., Lee H., Tiwari S., Ecelbarger C., Chronic insulin infusion down-regulates circulating and urinary nitric oxide (NO) levels despite molecular changes in the kidney predicting greater endothelial NO synthase activity in mice. Int. J. Mol. Sci. 2018, 19(10), 2880.
  26. Mitash N, Agnihotri S, Tiwari S, Agrawal V, Mandhani A. MicroRNA-21 could be a molecular marker to predict the recurrence of nonmuscle invasive bladder cancer. Indian J Urol. 2017 Oct-Dec;33(4):283-290. doi: 10.4103/iju.IJU_4_17.
  27. Mitash N, Tiwari S, Agnihotri S, Mandhani A. Bladder cancer: Micro RNAs as biomolecules for prognostication and surveillance. Indian J Urol. 2017 Apr-Jun;33(2):127-133. doi: 10.4103/0970-1591.203412. Review.
  28. To Study the Vitamin D Levels in Infertile Females and Correlation of Vitamin D Deficiency with AMH Levels in Comparison to Fertile Females. Lata I, Tiwari S, Gupta A, Yadav S, Yadav S. J Hum Reprod Sci. 2017 Apr-Jun;10(2):86-90. doi: 10.4103/jhrs.JHRS_105_16.
  29. Singh A, Chagtoo M, Tiwari S, George N, Chakravarti B, Khan, Lakshmi S, Godbole MM. Inhibition of Inositol 1, 4, 5-trisphosphate receptors induce breast cancer cell death through deregulated autophagy and cellular bioenergetics. J Cell Biochem 2017. 118(8):2333-2346.
  30. Chagtoo M., George N., Pathak N., Tiwari S,. Godbole M and Yury L. Inhibition of intracellular type 10 adenylyl cyclase protects cortical neurons against reperfusion-induced mitochondrial injury and apoptosis. Molecular Neurobiology 2018 Mar;55(3):2471-2482. doi: 10.1007/s12035-017-0473-y
  31. Singh RS, Chaudhary DK, Mohan A, Kumar P, Chaturvedi, CP, Elecbarger CA, Godbole MM, Tiwari S* Greater efficacy of atorvastatin versus a non-statin lipid-lowering agent against renal injury: potential role as a histone deacetylase inhibitor. Second review with Scientific Reports 2016 (Nature Publishing) Nov 30;6:38034. doi: 10.1038/srep38034.
  32. Li L, Byrd M, Doh K, Dixon PD, Lee H, Tiwari S, Ecelbarger CM. Absence of renal hypertrophy in fructose-fed proximal-tubule-select insulin receptor (IR), insulin-like-growth-factor receptor (IGF1R) double knockout mice. Physiological Reports 2016–Dec;4(23). pii: e13052.
  33. Pandey, G. Shankar K, Makhija E, Gaikwad A, Ecelbarger CM, Mandhani A, Srivastava A, Tiwari S*. "Reduced insulin receptor expression enhances proximal tubule gluconeogenesis." J Cell Biochem 2016. Jun 20. doi: 10.1002/jcb.25632.
  34. Tripathi R , Singh P, Singh A , Chagtoo M , Khan S, Tiwari S, Agarwal G, Meeran SM , Godbole MM* Zoledronate and Molecular Iodine Cause Synergistic Cell Death in Triple Negative Breast Cancer through Endoplasmic Reticulum Stress. Nutr Cancer 2016 Apr 26:1-10.
  35. Mohan A, Singh RS, Kumari M, Garg D, Upadhyay A, Ecelbarger CE, Tripathy S and Tiwari S* Urinary Exosomal microRNA-451-5p Is a Potential Early Biomarker of Diabetic Nephropathy in Rats. PLoS ONE 2016 Apr 2111(4): e0154055. doi: 10.1371/journal.pone.
  36. Mitash N, Agnihotri S, Mittal B, Tiwari S and Mandhani A. Molecular cystoscopy: Micro-RNAs could be a marker for identifying genotypic changes for transitional cell carcinoma of the urinary bladder Indian Journal of Urology 2016 Apr-Jun;32(2):149-53. DOI:10.4103/0970-1591.174775.
  37. Mohan A, Upadhyay. A., Godbole MM, Bhatia E andi Tiwari S*. "Wilms’ Tumor-1 (WT1) Protein in Urinary Exosomes Predicts Risk of Developing Proteinuria in Type-1 Diabetes." Journal of Diabetes & Metabolism 2015 6(3): 510.
  38. Pandey, G., E. Makhija, N. George, B. Chakravarti, M. M. Godbole, C. M. Ecelbarger and Tiwari S*. "Insulin regulates nitric oxide production in the kidney collecting duct cells." J Biol Chem 2015; 290(9): 5582-5591.
  39. Gautam J, Choudhary D, Khedgikar V, Kushwaha P, Singh RS, Singh D, Tiwari S, Trivedi R*. Micro-architectural changes in cancellous bone differ in female and male C57BL/6 mice with high-fat diet-induced low bone mineral density. Br J Nutr. 2014 28;111(10):1811-21.
  40. Tiwari S*, Singh RS, Li L, Tsukerman S, Godbole M, Pandey G, Ecelbarger CM Deletion of the insulin receptor in the proximal tubule promotes hyperglycemia. J Am Soc Nephrol 2013 Jul;24(8):1209-14.
  41. Kalani A, Mohan A, Godbole MM, Bhatia E, Gupta A, Sharma R. K, and Tiwari S*. Wilm’s tumor-1 protein levels in urinary exosomes from diabetic patients with or without proteinuria. PLoS One. 2013;8(3):e60177.
  42. Li L, Garikepati RM, Tsukerman S, Kohan D, Wade J, Tiwari S and Ecelbarger CM*. Reduced ENaC activity and blood pressure in mice with genetic knockout of the insulin receptor in the renal collecting duct. AJP –Renal Physiol. 2013 Feb;304(3):F279-88
  43. Li L, Garikepati RM, Tsukerman S, Tiwari S, Ecelbarger CM*. Salt-sensitivity of nitric oxide generation and blood pressure in mice with targeted knockout of the insulin receptor from the renal tubule. AJP-Regul Integr Comp Physiol. 2013 Sep 1;303(5):R505-12.
  44. Godbole MM*, Rao G, Paul BN, Mohan V, Singh P, Khare D, Babu S, Nath A, Singh PK, Tiwari S. Prenatal iodine deficiency results in structurally and functionally immature lungs in neonatal rats. AJP-Lung Cell Mol Physiol. 2012 2012 May 15;302(10):L1037-43
  45. Singh P, Godbole MM*, Rao G, Annarao S, Mitra K, Roy R, Ingle A, Agarwal G and Tiwari S. Inhibition of autophagy stimulate molecular Iodine-induced apoptosis in hormone independent breast tumors. BBRC 2011 Nov 11; 415(1):181-6.
  46. Ecelbarger CM, Rash A, Halagappa VK, Sinha RK and Tiwari S*. Candesartan markedly attenuate renal disease in the obese Zucker rat despite its propensity to worsen glucose tolerance. Mediators of Inflammation. 2010; 841343
  47. Tiwari S., Li L., Riazi S., Madala Halagappa VK, and Ecelbarger CM*. Sex differences in adaptive down-regulation of pre-macula densa sodium transporters with Ang II infusion in mice. AJP- Renal Physiol. 2010 Jan;298(1):F187-95
  48. Tiwari S., Li L., Riazi S., Madala Halagappa VK, and Ecelbarger CM*. Sex and age results in differential regulation of the renal thiazide-sensitive NaCl cotransporter and the epithelial sodium channel in angiotensin II-infused mice. Am J Nephrol. 2009, Oct 21; 30(6): 554-562
  49. Klein JD, Rash A., Sands JM, Ecelbarger CM and Tiwari S*. Candesartan differentially regulates distal sodium transporters and channel subunits in cortex versus medulla in streptozotocin-induced diabetic rats Journal of Epithelial Biology and Pharmacology. 2009, 2: 23-29
  50. Eileen Regina Blasi ER., Heyen J. Hemkens M., McHarg A., Ecelbarger CM and Tiwari S*. Effects of chronic PPAR-agonist treatment on cardiac structure and function, blood pressure and kidney in healthy Sprague-Dawley rats. PPAR Research. 2009; 2009:237865.
  51. Riazi S., Tiwari S., Rash A., Shrama N. and Ecelbarger CM*. The abundance and activity of the Na-K-2Cl cotransporter (NKCC2) is increased by high-fat feeding in Fisher 344 X Brown Norway (F1) rats. Am J Physiol-Renal Physiol. 2009; 296(4): F 762-70.
  52. Tiwari S*, Sharma N, Gill PS, Igarashi P, Kahn RC, Wade JB, and Ecelbarger CA. Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor. Proc Natl Acad Sci, U.S.A. (PNAS) 2008; 105: 6469-74. (**Manuscript assessed by ‘Faculty of 1000’)
  53. Tiwari S*, Blasi E, Heyen JR, McHarg AD, and Ecelbarger CA. Time course of AQP-2 and ENaC regulation in the kidney in response to PPAR agonists associated with marked edema in rats. Pharmacological Research. 2008; 57: 383-92.
  54. Madala Halagappa VK, Tiwari S, Riazi S, Hu X and Ecelbarger CA*. Chronic candesartan alters expression and activity of NKCC2, NCC, and ENaC in the obese Zucker rat. AJP- Renal Physiol. 2008; 294: F1222-31.
  55. Hu J, Tiwari S, Riazi S, Hu X, Wang X, and Ecelbarger CM*. Regulation of angiotensin II type I receptor (AT1R) protein levels in the obese Zucker rat kidney and urine. Exp and Clin Hypertension. 2009; Feb;31(1):49-63.
  56. Song J, Liu H., Ressom H, Tiwari S and Ecelbarger CA*. Chronic rosiglitazone therapy normalizes expression of ACE1, SCD1 and other genes in the kidney of obese Zucker rats as determined by microarray analysis. Exp and Clin Endocrinol & Diabetes 2008; 116: 315-325.
  57. Tiwari S, Riazi S, and Ecelbarger CA*. Insulin's impact on renal sodium transport and blood pressure in health, obesity and diabetes. AJP- Renal Physiol. 2007; 293: F974-84.
  58. Tiwari S*, Nordquest L, Halagappa VKM, and Ecelbarger CA. Trafficking of the ENaC subunits in response to acute insulin in mouse kidney. AJP- Renal Physiol. 2007; 293: F178-85.
  59. Tiwari S*, Halagappa VK, Riazi S, Hu X, and Ecelbarger CA. Reduced expression of insulin receptors in the kidneys of insulin-resistant rats. J Am Soc Nephrol (JASN) 2007; 18: 2661-71.
  60. Riazi S., Khan O., Tiwari S., Hu X., Ecelbarger CA*. Rosiglitazone regulates ENaC and Na-K-2Cl cotransporter (NKCC2) abundance in the obese Zucker rat. Am J Nephrol. 2006; 26: 245-57.
  61. Tiwari S, Hu X, Sugimura Y, Verbalis JG and Ecelbarger CA*. Increased renal α-ENaC and NCC abundance, as well as, elevated blood pressure is independent of hyperaldosteronism in vasopressin escape. AJP- Renal Physiol. 2006; 291: F49-57.
  62. Ecelbarger CA* and Tiwari S. Sodium transporters in the distal nephron and disease implications. Current Hypertension Reports. 2006; 8: 158-65.
  63. Tiwari S, Zhang Y, Heller J, Abernethy DR, and Soldatov NM*. Atherosclerosis-related molecular alteration of the human calcium channel 1C subunit. Proc Natl Acad Sci, U S A. (PNAS) 2006; 103: 17024-29.
  64. Kobrinsky E, Tiwari S, Maltsev VA, Harry JB, Lakatta E, Abernethy DR, Soldatov NM*. Differential role of the alpha1C subunit tails in regulation of the CaV1.2 channel by membrane potential, beta subunits, and Ca2+ ions. J Biol Chem. (JBC) 2005; 280:12474-85.
  65. Song J, Hu X, Riazi S, Tiwari S, Wade J, Ecelbarger CA*. Regulation of Blood Pressure, the Epithelial Sodium Channel (ENaC), and the Na-Cl cotransporter (NCC) by Chronic Insulin Infusion in Rats. AJP-l Renal Physiol. 2005; 290: F1055-64.
  66. Tiwari S, Gupta SK, Kumar K, Trivedi R, & Godbole MM*. Simultaneous exposure of excess fluoride and calcium deficiency alters VDR, CaR, and calbindin D 9 k mRNA levels in rat duodenal mucosa. Calcif Tissue Int. 2004; 75: 313-20.
  67. Mehrotra M, Gupta SK*, Tiwari S, Agarwal G, K Kumar, Awasthi PK & Godbole MM. Effect of oophorectomy on expression of calcium sensing receptor mRNA in rat duodenal mucosa. Indian J Exp Biol. 2003; 41: 41-46.
  68. Tiwari S, Gupta SK*, Mehrotra M, Agarwal G, Awasthi PK& Godbole MM. Short term androgen deprivation does not alter CaR and VDR mRNA expression in duodenal mucosa in male rats. Indian J Exp Biol. 2002; 40: 780-84.

Book chapter

  1. Ecelbarger CM, Chaudhary DK, Lee H, Tiwari S. (2017) Molecular Mechanisms of Body Water Homeostasis. In: D.N. Granger and J.P. Granger (Series Editors), Colloquium Series on Integrated Systems Physiology: Vol. 67. San Rafael, CA/USA: Morgan & Claypool Life Sciences Publishers. doi: 10.4199/C00144ED1V01Y201610ISP067 (eBook)
  2. Ecelbarger CA and Tiwari S. Molecular Biology and Gene Regulation. In Textbook of Nephro-Endocrinology (Edited by Singh A. and Williams G.) Chapter 17 (Elsevier, December 2008). (Book Chapter)